Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838373 | 0.83 | NR1H4 (0.50) | ELANENR1H4KDM4EPKM | |
| SCHEMBL3835251 | 0.82 | NR1H4 (0.44) | ELANENR1H4KDM4E | |
| SCHEMBL5721660 | 0.81 | NR1H4 (0.45) | ELANENR1H4KDM4ECYP2C19 | |
| SCHEMBL4598886 | 0.81 | NR1H4 (0.43) | ELANENR1H4 | |
| SCHEMBL14677996 | 0.81 | NR1H4 (0.48) | ELANENR1H4 | |
| SCHEMBL4665640 | 0.80 | NR1H4 (0.44) | ELANENR1H4 | |
| SCHEMBL4618555 | 0.80 | NR1H4 (0.46) | ELANENR1H4 | |
| SCHEMBL5689568 | 0.80 | NR1H4 (0.42) | ELANENR1H4KDM4E | |
| SCHEMBL5709264 | 0.80 | NR1H4 (0.42) | ELANENR1H4KDM4E | |
| SCHEMBL4598052 | 0.80 | NR1H4 (0.51) | ELANENR1H4KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |