Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090432 | 0.82 | CYP2D6 (0.47) | CCR3MAOBCYP2D6 | |
| SCHEMBL6986640 | 0.82 | CYP2D6 (0.47) | CCR3MAOBCYP2D6 | |
| SCHEMBL21216506 | 0.82 | CYP2D6 (0.47) | CCR3MAOBCYP2D6 | |
| SCHEMBL21216483 | 0.80 | CYP2D6 (0.50) | CCR3CYP2D6 | |
| SCHEMBL14983625 | 0.80 | CYP2D6 (0.50) | CCR3CYP2D6 | |
| SCHEMBL21216481 | 0.80 | CYP2D6 (0.50) | CCR3CYP2D6 | |
| SCHEMBL22470627 | 0.78 | CCR3 (0.45) | CCR3MAOBCYP2D6 | |
| SCHEMBL6970404 | 0.78 | CCR3 (0.45) | CCR3MAOBCYP2D6 | |
| SCHEMBL16600579 | 0.78 | ALDH1A1 (0.50) | CCR3CYP2D6 | |
| SCHEMBL22623880 | 0.77 | CCR3 (0.42) | CCR3MAOBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296978-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002525-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |