Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655599 | 0.77 | POLB (0.63) | MAPTCNR1CNR2NAMPTTRPV1 | |
| Hydrochloric Acid SCHEMBL23246046 | 0.76 | POLB (0.66) | MAPTCNR1CNR2NAMPTTRPV1 | |
| SCHEMBL14934385 | 0.74 | CYP2D6 (0.60) | MAPTNAMPTEPHX2TRPV1TRPM8 | |
| SCHEMBL3072567 | 0.73 | MAPT (0.59) | MAPTCNR1CNR2NAMPTEPHX2 | |
| SCHEMBL4559682 | 0.72 | MAPT (0.73) | MAPTCNR1CNR2NAMPTEPHX2 | |
| SCHEMBL22568186 | 0.72 | TRPV1 (0.47) | MAPTCNR1CNR2NAMPTEPHX2 | |
| SCHEMBL4813571 | 0.71 | EPHX2 (0.61) | MAPTCNR1CNR2NAMPTEPHX2 | |
| SCHEMBL4813582 | 0.71 | EPHX2 (0.61) | MAPTCNR1CNR2NAMPTEPHX2 | |
| Hydrochloric Acid SCHEMBL28861578 | 0.71 | POLB (0.58) | MAPTCNR1CNR2NAMPTTRPV1 | |
| SCHEMBL25153745 | 0.71 | HSD17B10 (0.73) | NAMPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301484-A2 | CAPSAICIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2003-04-16 | — | — | EP | claimed |
| WO-2002008221-A2 | CAPSAICIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2002-01-31 | — | — | WO | claimed |