Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987025 | 0.93 | USP2 (0.51) | USP2MAPK1ALDH1A1HPGDMAPT | |
| SCHEMBL5210601 | 0.79 | KDM4E (0.56) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL6238397 | 0.77 | ALDH1A1 (0.54) | USP2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6989053 | 0.73 | ALDH1A1 (0.49) | USP2ALDH1A1MAPTPTGESALOX5 | |
| SCHEMBL6987911 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTTSHRKMT2AHSD17B10 | |
| SCHEMBL5210605 | 0.72 | CFTR (0.55) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL5211456 | 0.71 | HSD17B10 (0.73) | MAPK1ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL5808530 | 0.71 | ALDH1A1 (0.65) | ALDH1A1HPGDMAPTKDM4EKDM6B | |
| SCHEMBL5135859 | 0.70 | ALDH1A1 (0.55) | USP2MAPK1ALDH1A1TAS2R14HPGD | |
| SCHEMBL6268216 | 0.70 | MAPK1 (0.54) | USP2MAPK1MEP1BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |