Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6990511 | 1.00 | KDM4E (0.49) | KDM4EKMT2AALDH1A1GAALMNA | |
| Oxalic Acid SCHEMBL7002201 | 0.89 | HRH3 (0.57) | KDM4EKMT2AALDH1A1GAAHRH3 | |
| Oxalic Acid SCHEMBL6996106 | 0.89 | HRH3 (0.57) | KDM4EKMT2AALDH1A1GAAHRH3 | |
| Oxalic Acid SCHEMBL6997960 | 0.88 | HRH3 (0.61) | KDM4EALDH1A1HRH3 | |
| Oxalic Acid SCHEMBL6997413 | 0.88 | HRH3 (0.61) | KDM4EALDH1A1HRH3 | |
| Oxalic Acid SCHEMBL7001732 | 0.86 | KMT2A (0.49) | KDM4EKMT2AALDH1A1GAAHRH3 | |
| Oxalic Acid SCHEMBL6998748 | 0.86 | KMT2A (0.49) | KDM4EKMT2AALDH1A1GAAHRH3 | |
| Oxalic Acid SCHEMBL6996581 | 0.84 | HRH3 (0.48) | KDM4EKMT2AALDH1A1GAALMNA | |
| Oxalic Acid SCHEMBL7001883 | 0.84 | HRH3 (0.48) | KDM4EKMT2AALDH1A1GAALMNA | |
| Oxalic Acid SCHEMBL6998745 | 0.83 | KMT2A (0.60) | KMT2AHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |
| US-5981539-A | TREATMENT OF STROKE, ANOXIA, ISCHEMIA, MIGRAINE, PSYCHOSIS, EPILEPSY OR ANY OTHER CONVULSIVE DISORDER | NEUROSEARCH A/S (DK) | 1999-11-09 | — | — | US | disclosed |