Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6996581 | 1.00 | HRH3 (0.48) | HRH3KMT2AALDH1A1KDM4EMEN1 | |
| Oxalic Acid SCHEMBL7000093 | 0.93 | HRH3 (0.58) | HRH3KMT2AALDH1A1KDM4ELMNA | |
| Oxalic Acid SCHEMBL6990281 | 0.93 | HRH3 (0.58) | HRH3KMT2AALDH1A1KDM4ELMNA | |
| Oxalic Acid SCHEMBL6991838 | 0.90 | HRH3 (0.58) | HRH3KMT2AMEN1 | |
| Oxalic Acid SCHEMBL6987195 | 0.90 | RAB9A (0.53) | HRH3KMT2AALDH1A1KDM4ELMNA | |
| Oxalic Acid SCHEMBL6994186 | 0.90 | HRH3 (0.58) | HRH3KMT2AMEN1 | |
| Oxalic Acid SCHEMBL6997995 | 0.90 | RAB9A (0.53) | HRH3KMT2AALDH1A1KDM4ELMNA | |
| Oxalic Acid SCHEMBL6996106 | 0.88 | HRH3 (0.57) | HRH3KMT2AALDH1A1KDM4EMEN1 | |
| Oxalic Acid SCHEMBL6998745 | 0.88 | KMT2A (0.60) | HRH3KMT2AMEN1 | |
| Oxalic Acid SCHEMBL6987245 | 0.88 | KMT2A (0.60) | HRH3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |