SCHEMBL69877

SCHEMBL69877

O=C(O)c1ccc2c(c1)C(=O)c1c(C(=O)O)cccc1C2=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 10/20 0.73
ALDH1A1 P00352 4/20 0.73
L3MBTL1 Q9Y468 2/20 0.73
MAPT P10636 5/20 0.63
LMNA P02545 3/20 0.63
PTPRC P08575 2/20 0.63
POLB P06746 3/20 0.60
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
THRB P10828 2/20 0.53
RECQL P46063 2/20 0.53
MAPK1 P28482 2/20 0.53
TSHR P16473 2/20 0.51
HIF1A Q16665 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
SOS1 Q07889 1/20 0.51
HPGD P15428 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70489 1.00 TTR (0.73) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL599326 0.92 TTR (0.67) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL10526597 0.92 TTR (0.67) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL10492712 0.92 POLB (0.70) TTRALDH1A1L3MBTL1MAPTLMNA
Anthraquinone SCHEMBL8941397 0.85 ALDH1A1 (1.00) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL461660 0.85 ALDH1A1 (1.00) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL26187220 0.84 TTR (1.00) TTRALDH1A1L3MBTL1MAPTLMNA
Hydrochloric Acid SCHEMBL8675457 0.83 ALDH1A1 (0.96) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL9717021 0.83 TTR (0.71) TTRALDH1A1L3MBTL1MAPTLMNA
SCHEMBL18717242 0.83 TTR (0.71) TTRALDH1A1L3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TTR 3513/4885ALDH1A1 1882/4885L3MBTL1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.