Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61275 | 1.00 | METAP1 (0.46) | METAP1GABRR1CYP1A2METAP2HPGD | |
| SCHEMBL17590498 | 1.00 | METAP1 (0.46) | METAP1GABRR1CYP1A2METAP2HPGD | |
| SCHEMBL27488750 | 0.91 | ACE2 (0.44) | METAP1GABRR1CYP1A2METAP2HPGD | |
| SCHEMBL6156004 | 0.89 | CYP1A2 (0.45) | METAP1GABRR1CYP1A2SIGMAR1BLM | |
| SCHEMBL27486952 | 0.89 | ACE2 (0.46) | METAP1GABRR1CYP1A2METAP2SLC1A3 | |
| SCHEMBL18050478 | 0.89 | CYP1A2 (0.45) | METAP1GABRR1CYP1A2SIGMAR1BLM | |
| SCHEMBL27601862 | 0.85 | METAP1 (0.41) | METAP1METAP2HPGDSLC1A3SLC1A2 | |
| SCHEMBL28740646 | 0.85 | ACE2 (0.46) | METAP1GABRR1CYP1A2SLC1A3SLC1A2 | |
| SCHEMBL27602009 | 0.83 | METAP1 (0.39) | METAP1GABRR1CYP1A2METAP2BLM | |
| SCHEMBL931400 | 0.82 | METAP1 (0.49) | METAP1CYP1A2METAP2HPGDSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324974-A2 | DRUGS FOR DIABETES | Nicox S.A. (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030867-A2 | DRUGS FOR DIABETES | NICOX S.A. (FR) | 2002-04-18 | — | — | WO | disclosed |