Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13582 | 1.00 | METAP1 (0.49) | METAP1EPHX1METAP2ALOX5HPGD | |
| SCHEMBL17590498 | 0.82 | METAP1 (0.46) | METAP1METAP2HPGDCYP1A2SIGMAR1 | |
| SCHEMBL6987701 | 0.82 | METAP1 (0.46) | METAP1METAP2HPGDCYP1A2SIGMAR1 | |
| SCHEMBL61275 | 0.82 | METAP1 (0.46) | METAP1METAP2HPGDCYP1A2SIGMAR1 | |
| SCHEMBL4793949 | 0.81 | CPN1 (0.38) | SIGMAR1 | |
| SCHEMBL370568 | 0.80 | EPHX1 (0.49) | EPHX1ALOX5 | |
| SCHEMBL9099 | 0.80 | EPHX1 (0.49) | EPHX1ALOX5 | |
| SCHEMBL13235909 | 0.80 | METAP1 (0.43) | METAP1EPHX1METAP2HPGDCYP1A2 | |
| SCHEMBL11410546 | 0.80 | MAPT (0.40) | METAP1EPHX1METAP2CYP1A2SIGMAR1 | |
| SCHEMBL13076173 | 0.79 | METAP1 (0.43) | METAP1EPHX1METAP2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |