Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635670 | 0.86 | F2 (0.74) | F2 | |
| SCHEMBL7670676 | 0.83 | F2 (0.69) | F2 | |
| SCHEMBL6634233 | 0.82 | F2 (0.62) | F2 | |
| Hydrochloric Acid SCHEMBL6977321 | 0.80 | F2 (0.67) | F2 | |
| SCHEMBL6974717 | 0.80 | F2 (0.62) | F2 | |
| SCHEMBL6987739 | 0.80 | F2 (0.62) | F2 | |
| SCHEMBL6985103 | 0.79 | F2 (0.66) | F2 | |
| SCHEMBL6983757 | 0.79 | F2 (0.63) | F2 | |
| SCHEMBL6986249 | 0.79 | F2 (0.61) | F2 | |
| Hydrochloric Acid SCHEMBL6986105 | 0.79 | F2 (0.62) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220844-B1 | ARYL SULFONAMIDE-SUBSTITUTED BENZIMIDAZOL DERIVATIVES THEREOF AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-1220844-A1 | ARYL SULFONAMIDE-SUBSTITUTED BENZIMIDAZOL DERIVATIVES THEREOF AS TRYPTASE INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2002-07-10 | — | — | EP | disclosed |
| US-6365584-B1 | FOR PROPHYLAXIS AND THERAPY OF INFLAMMATORY AND/OR ALLERGIC DISEASES, LUNG FIBROSIS, FIBROSING ALVEOLITIS AND SCARRING, COLLAGENOSES SUCH AS LUPUS ERYTHEMATODES AND SCLERODERMIA AS WELL AS ARTERIOSCLEROSIS, PSORIASIS AND NEOPLASM | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-04-02 | — | — | US | disclosed |
| WO-2001023360-A1 | ARYL SULFONAMIDE-SUBSTITUTED BENZIMIDAZOL DERIVATIVES THEREOF AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-04-05 | — | — | WO | disclosed |