Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987946 | 0.79 | GHSR (0.56) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL11033138 | 0.77 | EPHX1 (0.84) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL11034317 | 0.77 | EPHX1 (0.84) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL6438783 | 0.77 | EPHX1 (0.84) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL14429911 | 0.73 | GHSR (0.70) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL13804544 | 0.71 | EPHX1 (0.74) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL13804536 | 0.71 | EPHX1 (0.74) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL7270458 | 0.71 | EPHX1 (0.74) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL8756663 | 0.71 | EPHX1 (0.74) | EPHX1ALDH1A1HTTEPHX2GHSR | |
| SCHEMBL6013414 | 0.71 | EPHX1 (0.74) | EPHX1ALDH1A1HTTEPHX2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328512-A2 | CYCLYLAMINE SULFONAMIDES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002006221-A2 | CYCLYLAMINE SULFONAMIDES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |