Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988195 | 1.00 | KDM4E (0.50) | KDM4EKDM4CALBMEN1KMT2A | |
| SCHEMBL6995099 | 0.84 | ADORA2A (0.56) | KDM4EALBMEN1KMT2AMAPT | |
| SCHEMBL6995096 | 0.84 | ADORA2A (0.56) | KDM4EALBMEN1KMT2AMAPT | |
| SCHEMBL6990038 | 0.84 | ALB (0.50) | KDM4EALBMEN1KMT2AMAPT | |
| SCHEMBL6990043 | 0.84 | ALB (0.50) | KDM4EALBMEN1KMT2AMAPT | |
| SCHEMBL6991270 | 0.79 | KMT2A (0.58) | KDM4EKDM4CALBMEN1KMT2A | |
| SCHEMBL6991265 | 0.79 | KMT2A (0.58) | KDM4EKDM4CALBMEN1KMT2A | |
| SCHEMBL6990822 | 0.78 | ALB (0.47) | KDM4EALBMEN1KMT2AMAPT | |
| SCHEMBL6990816 | 0.78 | ALB (0.47) | KDM4EALBMEN1KMT2AMAPT | |
| SCHEMBL6993353 | 0.76 | MEN1 (0.52) | ALBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |