Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990822 | 1.00 | ALB (0.47) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6988902 | 0.82 | ABL1 (0.51) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6988897 | 0.82 | ABL1 (0.51) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6995096 | 0.81 | ADORA2A (0.56) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6995099 | 0.81 | ADORA2A (0.56) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6990043 | 0.78 | ALB (0.50) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6988192 | 0.78 | KDM4E (0.50) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6988195 | 0.78 | KDM4E (0.50) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6990038 | 0.78 | ALB (0.50) | ALBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6989039 | 0.76 | ALB (0.43) | ALBERN1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |