Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992992 | 0.99 | L3MBTL1 (0.57) | L3MBTL1TP53MAPTPOLBS1PR1 | |
| SCHEMBL7078173 | 0.82 | MAPT (0.52) | L3MBTL1TP53MAPTPOLBLMNA | |
| SCHEMBL7083964 | 0.81 | MAPT (0.53) | L3MBTL1TP53MAPTPOLBLMNA | |
| SCHEMBL8311929 | 0.77 | L3MBTL1 (0.72) | L3MBTL1TP53MAPTPOLBCASP3 | |
| SCHEMBL7076779 | 0.75 | MAPT (0.52) | L3MBTL1TP53MAPTPOLBLMNA | |
| SCHEMBL7081126 | 0.75 | MAPT (0.51) | L3MBTL1TP53MAPTPOLBLMNA | |
| SCHEMBL13130238 | 0.74 | L3MBTL1 (1.00) | L3MBTL1TP53MAPTPOLBCASP3 | |
| SCHEMBL7080917 | 0.74 | MAPT (0.53) | L3MBTL1TP53MAPTPOLBLMNA | |
| SCHEMBL6992939 | 0.72 | MAPT (0.48) | L3MBTL1TP53MAPTPOLBLMNA | |
| SCHEMBL19287155 | 0.72 | L3MBTL1 (0.64) | L3MBTL1TP53MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |