Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988655 | 1.00 | KMT2A (0.49) | KMT2ASHMT2MMEPOLBHTT | |
| SCHEMBL6481411 | 0.86 | KMT2A (0.47) | KMT2ASHMT2MMEPOLBHTT | |
| SCHEMBL7960296 | 0.82 | LPAR1 (0.50) | KMT2ALPAR1ALDH1A1 | |
| SCHEMBL8473051 | 0.81 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL362211 | 0.81 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL7885098 | 0.81 | PTGS2 (0.64) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL5541713 | 0.76 | LPAR1 (0.49) | KMT2APOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL4156225 | 0.76 | MME (0.64) | MMEPOLBLTA4HACE | |
| SCHEMBL2251625 | 0.76 | HPGD (0.70) | KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL2251629 | 0.76 | HPGD (0.70) | KMT2AL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |