Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143967 | 0.77 | DAO (0.38) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL27346071 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1TP53GLAPARP1 | |
| SCHEMBL17897636 | 0.71 | P2RX7 (0.36) | KDM4EPARP1P2RX7SMN1; SMN2HSD17B10 | |
| SCHEMBL21738239 | 0.70 | — | — | |
| SCHEMBL16654409 | 0.69 | DAO (0.33) | ALDH1A1GLADAO | |
| SCHEMBL25044537 | 0.68 | DAO (0.50) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL10679161 | 0.68 | NOTUM (0.44) | DAO | |
| SCHEMBL14407007 | 0.68 | DAO (0.50) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL27298566 | 0.68 | KDM4E (0.44) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL30761205 | 0.66 | DPYD (0.42) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335903-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002042275-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
| CN-1034715-A | N-cyanogen methyl-2-pyridinone insecticides | DOW CHEMICAL CO (US) | 1989-08-16 | — | — | CN | disclosed |