Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245687 | 0.86 | TSHR (0.37) | TSHRMETAP1HPGDSMPD1FDPS | |
| Ammonia Solution, Strong SCHEMBL28245230 | 0.85 | TSHR (0.36) | TSHRMETAP1HPGDSMPD1FDPS | |
| SCHEMBL7759987 | 0.81 | TSHR (0.36) | TSHRHPGD | |
| SCHEMBL6988087 | 0.80 | TSHR (0.33) | TSHRMETAP1SMPD1FDPS | |
| SCHEMBL1068091 | 0.78 | TSHR (0.39) | TSHRHPGD | |
| SCHEMBL28245219 | 0.78 | TSHR (0.45) | TSHRHPGDSMPD1FDPS | |
| SCHEMBL6790640 | 0.77 | SMPD1 (0.46) | TSHRMETAP1HPGDSMPD1FDPS | |
| SCHEMBL10623140 | 0.77 | TSHR (0.36) | TSHRHPGDSMPD1 | |
| SCHEMBL1081569 | 0.77 | SMPD1 (0.50) | TSHRHPGDSMPD1FDPS | |
| SCHEMBL28865008 | 0.77 | TSHR (0.44) | TSHRHPGDSMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751161-B1 | Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin | MITSUI CHEMICALS INC (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-5736609-A | A POLYTHIO COMPOUND CONTAINING AT LEAST TWO MERCAPTO GROUPS, A POLYISO(THIO)CYANATE COMPOUND, AND A COMPOUND HAVING TWO OR MORE UNSATURATED REACTIVE GROUPS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0751161-A2 | Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-01-02 | — | — | EP | disclosed |