Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583209 | 0.88 | TSHR (0.36) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL1507509 | 0.85 | TSHR (0.40) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL36436 | 0.82 | TSHR (0.41) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL6988748 | 0.81 | TSHR (0.33) | TSHRHPGD | |
| SCHEMBL27590135 | 0.80 | TSHR (0.40) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL4256290 | 0.80 | TSHR (0.35) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28343973 | 0.80 | TSHR (0.40) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL147629 | 0.79 | TSHR (0.45) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL19583210 | 0.78 | TSHR (0.39) | TSHRHPGDALDH1A1TP53CYP3A4 | |
| SCHEMBL19583244 | 0.78 | TSHR (0.38) | TSHRHPGDALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795580-B1 | VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR | NIPPON ZEON CO (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5852093-A | Vulcanizable rubber composition, seal used in dynamic state, and sealing material | NIPPON ZEON CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0704480-B1 | Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber | NIPPON ZEON CO (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5683819-A | Composite of highly saturated nitrile rubber with fiber, and belt composed thereof | NIPPON ZEON CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0704479-B1 | Composite of highly saturated nitrile rubber with fiber, and belt composed thereof | NIPPON ZEON CO (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0704459-B1 | Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition | NIPPON ZEON CO (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0795580-A1 | VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR | NIPPON ZEON CO., LTD. (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5651995-A | Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition | NIPPON ZEON CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5556919-A | Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber | NIPPON ZEON CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0704459-A1 | Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition | NIPPON ZEON CO., LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704480-A1 | Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber | NIPPON ZEON CO., LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704479-A1 | Composite of highly saturated nitrile rubber with fiber, and belt composed thereof | NIPPON ZEON CO., LTD. (JP) | 1996-04-03 | — | — | EP | disclosed |