Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.60 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515448 | 0.93 | P2RY12 (0.60) | P2RY12USP28 | |
| SCHEMBL7003219 | 0.92 | P2RY12 (0.57) | P2RY12TYRO3MERTKGAS6USP28 | |
| SCHEMBL7514827 | 0.89 | P2RY12 (0.57) | P2RY12USP28 | |
| SCHEMBL7510403 | 0.89 | P2RY12 (0.58) | P2RY12 | |
| SCHEMBL7513822 | 0.89 | P2RY12 (0.57) | P2RY12USP28 | |
| SCHEMBL6999351 | 0.88 | P2RY12 (0.58) | P2RY12USP28 | |
| SCHEMBL6997872 | 0.88 | P2RY12 (0.68) | P2RY12 | |
| Bicarbonate SCHEMBL7510959 | 0.88 | P2RY12 (0.73) | P2RY12USP28 | |
| SCHEMBL7510570 | 0.87 | P2RY12 (0.58) | P2RY12 | |
| SCHEMBL7515280 | 0.87 | P2RY12 (0.66) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056749-B1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LTD (GB) | 2003-02-19 | — | — | EP | claimed |