Methacrylic Acid

SCHEMBL6988853

C=C(C)C(=O)O.C=C(C)C(=O)OCC(CC)S(=O)(=O)O.C=C(C)C(=O)OCCCC

nearest known ligand 0.51

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	4/20	0.51

▸	THRB	P10828	1/20	0.39

▸	POLB	P06746	1/20	0.39

▸	APEX1	P27695	1/20	0.39

▸	HTT	P42858	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.37

▸	HPGD	P15428	1/20	0.33

▸	RECQL	P46063	1/20	0.33

▸	HCAR2	Q8TDS4	1/20	0.32

▸	ATM	Q13315	1/20	0.32

▸	STS	P08842	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Methacrylic Acid SCHEMBL8861203	0.90	TSHR (0.49)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL8086434	0.86	TSHR (0.53)	TSHRTHRBALDH1A1RECQL
SCHEMBL14761131	0.84	TSHR (0.52)	TSHRTHRBALDH1A1RECQL
Styrene SCHEMBL6990959	0.84	TSHR (0.41)	TSHRPOLBAPEX1HTTTDP1
Methacrylic Acid SCHEMBL9422682	0.81	TSHR (0.75)	TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL8427966	0.81	TSHR (0.75)	TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL8406971	0.81	TSHR (0.75)	TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL462262	0.81	TSHR (0.75)	TSHRTHRBPOLBAPEX1HTT
SCHEMBL5057261	0.80	TSHR (0.47)	TSHRTHRBTDP1ALDH1A1RECQL
SCHEMBL27497939	0.80	TSHR (0.51)	TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0831365-B1	Imaging element containing an electrically-conductive polymer blend	EASTMAN KODAK CO (US)	2003-01-02	—	—	EP	claimed