Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14761131 | 0.98 | TSHR (0.52) | TSHRTHRBALDH1A1RECQL | |
| Methacrylic Acid SCHEMBL8861203 | 0.95 | TSHR (0.49) | TSHRTHRBALDH1A1RECQL | |
| Methacrylic Acid SCHEMBL6988853 | 0.86 | TSHR (0.51) | TSHRTHRBALDH1A1RECQL | |
| SCHEMBL29224043 | 0.86 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL5057261 | 0.83 | TSHR (0.47) | TSHRTHRBALDH1A1RECQL | |
| SCHEMBL27867536 | 0.83 | THRB (0.47) | TSHRTHRBALDH1A1RECQL | |
| Ammonia Solution, Strong SCHEMBL28050132 | 0.81 | THRB (0.46) | TSHRTHRBALDH1A1RECQL | |
| SCHEMBL15223842 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1RECQL | |
| SCHEMBL27497939 | 0.80 | TSHR (0.51) | TSHRTHRBALDH1A1RECQL | |
| SCHEMBL10949798 | 0.79 | TSHR (0.59) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699908-B1 | Immunoassay elements having stable leuco dye coatings | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-0699905-B1 | Leuco dye coating compositions | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5714340-A | LAYER CONTAINING LABELED LIGAND, BEAD SPREADING LAYER, CROSSLINKED HYDROPHILIC POLYMER LAYER AND A SUPPORT | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0699905-A1 | Leuco dye coating compositions | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-03-06 | — | — | EP | disclosed |
| EP-0699908-A2 | Immunoassay elements having stable leuco dye coatings | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5496702-A | TRIARYLIMIDAZOLE DYES, NONIONIC SURFACTANTS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-03-05 | — | — | US | disclosed |