Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539649 | 0.93 | TP53 (0.32) | TP53TDP1TSHRSIGMAR1CHRNB2 | |
| SCHEMBL29677328 | 0.88 | TP53 (0.39) | TP53TDP1TSHRSIGMAR1MEN1 | |
| SCHEMBL7452828 | 0.88 | TP53 (0.39) | TP53TDP1TSHRSIGMAR1MEN1 | |
| SCHEMBL28499171 | 0.86 | TP53 (0.38) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL28498569 | 0.86 | TP53 (0.38) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL5623197 | 0.84 | TP53 (0.42) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL8928315 | 0.81 | TP53 (0.48) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL13575585 | 0.81 | TP53 (0.48) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL9170191 | 0.73 | NPSR1 (0.33) | TSHRSIGMAR1 | |
| SCHEMBL29389309 | 0.72 | KMT2A (0.58) | TP53TDP1TSHRMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739345-B1 | CYCLIC POLYAMINES | ANORMED INC (CA) | 2003-04-09 | — | — | EP | disclosed |
| US-5698546-A | Cyclic polyamines | JOHNSON MATTHEY PUBLIC LIMTED COMPANY (GB) | 1997-12-16 | — | — | US | disclosed |
| EP-0739345-A1 | CYCLIC POLYAMINES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018808-A1 | CYCLIC POLYAMINES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1995-07-13 | — | — | WO | disclosed |