Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29677328 | 1.00 | TP53 (0.39) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL28499171 | 0.98 | TP53 (0.38) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL28498569 | 0.98 | TP53 (0.38) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL3539649 | 0.89 | TP53 (0.32) | TP53TDP1TSHRSIGMAR1 | |
| SCHEMBL6988942 | 0.88 | TP53 (0.37) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL8928315 | 0.84 | TP53 (0.48) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL13575585 | 0.84 | TP53 (0.48) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL15443789 | 0.82 | TSHR (0.36) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL5623197 | 0.78 | TP53 (0.42) | TP53TDP1TSHRMEN1GAA | |
| SCHEMBL29389309 | 0.75 | KMT2A (0.58) | TP53TDP1TSHRMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |