Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.77 |
| ▸ | ADRA1D | P25100 | 20/20 | 0.77 |
| ▸ | HTR1B | P28222 | 20/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997290 | 0.95 | HTR1A (0.81) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6988254 | 0.94 | HTR1A (0.77) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6999672 | 0.94 | HTR1A (0.77) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722206 | 0.93 | HTR1A (0.76) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7719649 | 0.93 | HTR1A (0.76) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6999374 | 0.91 | HTR1A (0.72) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6992592 | 0.90 | HTR1A (0.73) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722136 | 0.90 | HTR1A (0.71) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6995317 | 0.89 | HTR1A (0.84) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722147 | 0.88 | HTR1A (0.83) | HTR1AADRA1DHTR1BADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927184-B1 | 3-SUBSTITUTED PYRIDO 4',3':4,5]THIENO 2,3-D]PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2003-10-22 | — | — | EP | disclosed |