Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.38 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | KDM5C | P41229 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989293 | 0.94 | KDM4C (0.47) | CYP11B1CYP11B2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6233370 | 0.76 | KDM5A (0.39) | CYP11B1CYP11B2KMT2AKDM4EKDM5B | |
| SCHEMBL16824151 | 0.76 | HPGD (0.51) | SMN1; SMN2KMT2AMEN1HTTHPGD | |
| SCHEMBL6989792 | 0.75 | MEN1 (0.45) | CYP11B1CYP11B2KMT2AMEN1HTT | |
| SCHEMBL6989789 | 0.74 | KDM4C (0.53) | KMT2AMEN1LMNAKDM4EKDM5B | |
| SCHEMBL6985002 | 0.73 | KDM4E (0.42) | KDM4EKDM5BKDM5AKDM5CALDH1A1 | |
| SCHEMBL5210831 | 0.72 | KMT2A (0.67) | SMN1; SMN2KMT2AMEN1HTTHPGD | |
| SCHEMBL5210605 | 0.72 | CFTR (0.55) | KMT2AMEN1TSHRKDM4EKDM5B | |
| SCHEMBL5214358 | 0.70 | PPARG (0.55) | KMT2ALMNATSHRALDH1A1MAPT | |
| SCHEMBL6233367 | 0.70 | KDM4C (0.48) | KDM4EKDM5BKDM5AKDM5CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |