Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985002 | 0.92 | KDM4E (0.42) | KDM5BKDM4EKDM5AKDM5CMAPT | |
| SCHEMBL6235518 | 0.86 | ALDH1A1 (0.49) | RAB9ANPC1KDM5BKDM4EKDM5A | |
| SCHEMBL6239726 | 0.86 | ALDH1A1 (0.46) | RAB9ANPC1KDM5BKDM4EKDM5A | |
| SCHEMBL6985934 | 0.86 | MAPT (0.43) | RAB9ATDP1NPC1KDM5BKDM4E | |
| SCHEMBL5210605 | 0.85 | CFTR (0.55) | MEN1KMT2ATDP1KDM5BKDM4E | |
| SCHEMBL6985000 | 0.85 | KDM4C (0.50) | KDM5BKDM4EKDM5AKDM5CMAPT | |
| SCHEMBL6990114 | 0.83 | LPAR1 (0.49) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL6986949 | 0.82 | SLC2A1 (0.48) | LPAR1LPAR5 | |
| SCHEMBL6989317 | 0.81 | SMN1; SMN2 (0.47) | RAB9ANPC1CA1CA2CA9 | |
| SCHEMBL6235516 | 0.81 | KDM4C (0.49) | MEN1KMT2AKDM5BKDM4EKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |