Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 7/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6994782 | 0.99 | KCNH3 (0.37) | BLMMEN1KMT2AKCNH3MERTK | |
| SCHEMBL6998561 | 0.92 | BLM (0.38) | BLMMEN1KMT2AKCNH3MERTK | |
| Hydrochloric Acid SCHEMBL6990611 | 0.91 | KCNH3 (0.38) | BLMMEN1KMT2AKCNH3MAPK1 | |
| SCHEMBL7000418 | 0.87 | GALR2 (0.35) | MEN1KMT2AMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6993369 | 0.87 | GALR2 (0.35) | MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL6963727 | 0.85 | MAPT (0.40) | BLMMEN1KMT2AKCNH3MAPK1 | |
| Hydrochloric Acid SCHEMBL6992610 | 0.84 | MAPT (0.39) | BLMMEN1KMT2AKCNH3MAPK1 | |
| Hydrochloric Acid SCHEMBL7001990 | 0.83 | KMT2A (0.40) | MEN1KMT2AMAPK1LMNATSHR | |
| SCHEMBL6995386 | 0.80 | GALR2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6993026 | 0.79 | GALR2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | claimed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | claimed |