Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCND1 | P24385 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31116761 | 1.00 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL7127296 | 0.80 | PRKD3 (0.50) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5661417 | 0.76 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5604900 | 0.76 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL2187570 | 0.76 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL23075523 | 0.76 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17072846 | 0.76 | PRKD3 (0.50) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL983397 | 0.76 | CDC7 (0.49) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL2410450 | 0.76 | TRAP1 (0.50) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL31310579 | 0.76 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445989-B | Phosphine ligand with indole skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2020-05-29 | — | — | CN | claimed |
| CN-107445989-A | A kind of Phosphine ligands of indoles skeleton and its preparation method and application | 香港理工大学深圳研究院 | 2017-12-08 | — | — | CN | claimed |
| CN-107445989-B | Phosphine ligand with indole skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2020-05-29 | — | — | CN | disclosed |
| WO-2020041369-A1 | METHODS FOR THE SYNTHESIS OF HETEROATOM CONTAINING POLYCYCLIC AROMATIC HYDROCARBONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-02-27 | — | — | WO | disclosed |
| CN-107445989-A | A kind of Phosphine ligands of indoles skeleton and its preparation method and application | 香港理工大学深圳研究院 | 2017-12-08 | — | — | CN | disclosed |
| WO-2015133807-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 주식회사 두산 | 2015-09-11 | — | — | WO | disclosed |
| EP-1303508-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |
| WO-2002006273-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-01-24 | — | — | WO | disclosed |