Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 9/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.37 |
| ▸ | NPY1R | P25929 | 7/20 | 0.37 |
| ▸ | NPY2R | P49146 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304374 | 0.82 | MC4R (0.39) | PDE4APDE4BPDE4CPDE4DPADI6 | |
| SCHEMBL8515668 | 0.77 | HDAC1 (0.45) | NPY4RNPY5RNPY1RNPY2RPDE4A | |
| SCHEMBL8342382 | 0.77 | MEN1 (0.43) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| SCHEMBL30743663 | 0.77 | FOLH1 (0.51) | NPY4RNPY5RNPY1RNPY2RMC4R | |
| SCHEMBL10420284 | 0.76 | HDAC1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL28274785 | 0.76 | MEN1 (0.43) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| Hydrochloric Acid SCHEMBL28274778 | 0.76 | MEN1 (0.43) | NPY4RNPY5RNPY1RNPY2RROCK2 | |
| Naphthylamine SCHEMBL27915557 | 0.75 | C3AR1 (0.46) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL31318380 | 0.74 | NPY4R (0.56) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL5598751 | 0.74 | NPY4R (0.52) | QRFPRNPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719779-B1 | SUBSTITUTED THIAZOLO [3,2-ALPHA]AZEPINE DERIVATIVE | EISAI CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6051705-A | HAVING INHIBITORY ACTIVITY AGAINST ANGIOTENSIN I CONVERTING ENZYME AND NEUTRAL ENDPEPTIDASE | EISAI CO., LTD. (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5789403-A | PEPTIDASE AND ACE ENZYME INHIBITORS | EISAI CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5679671-A | ANGIOTENSIN 1-CONVERTING ENZYME INHIBITOR, VASOPRESSIN ANTAGONISM AND ATRIAL NAUTRIURETIC PEPTIDE HYDROLASE INHIBITOR | EISAI CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0719779-A1 | SUBSTITUTED THIAZOLO [3,2-ALPHA]AZEPINE DERIVATIVE | Eisai Co., Ltd. (JP) | 1996-07-03 | — | — | EP | disclosed |
| EP-0671172-A1 | AMINO ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |