Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.39 |
| ▸ | MC5R | P33032 | 5/20 | 0.39 |
| ▸ | MC3R | P41968 | 5/20 | 0.39 |
| ▸ | MC1R | Q01726 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419724 | 0.87 | CTSG (0.31) | MC4RMC5RMC3RMC1RALDH1A1 | |
| SCHEMBL7642635 | 0.87 | MC4R (0.42) | MC4RMC5RMC3RMC1RDPP8 | |
| SCHEMBL6989412 | 0.82 | QRFPR (0.38) | MC4RMC3RMC1RPDE4APDE4B | |
| SCHEMBL27797839 | 0.82 | MC4R (0.38) | MC4RMC5RMC3RMC1RF10 | |
| SCHEMBL1673135 | 0.82 | MC4R (0.38) | MC4RMC5RMC3RMC1RF10 | |
| SCHEMBL9200915 | 0.82 | DPP8 (0.39) | MC4RMC5RMC3RMC1RDPP8 | |
| SCHEMBL7717724 | 0.82 | ALDH1A1 (0.44) | MC4RDPP8DPP9ALDH1A1MEN1 | |
| SCHEMBL22346178 | 0.82 | ALDH1A1 (0.44) | MC4RDPP8DPP9ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27842009 | 0.81 | ALDH1A1 (0.43) | MC4RDPP8DPP9ALDH1A1MEN1 | |
| SCHEMBL29094090 | 0.77 | OPRM1 (0.41) | MC4RMC5RMC3RMC1RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349199-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PERIODONTAL DISEASES | Akademia Medyczna Im. Piastow Slaskich We Wroclawiu (PL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010024702-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PERIODONTAL DISEASES | AKADEMIA MEDYCZNA IM. PIASTOW SLASKICH WE WROCLAWIU (PL) | 2010-03-04 | — | — | WO | disclosed |