Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123679 | 0.86 | NPC1 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5103142 | 0.75 | RXFP1 (0.52) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| Ethane SCHEMBL5123686 | 0.75 | NPC1 (0.51) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4470757 | 0.73 | NPC1 (0.44) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6989552 | 0.73 | PPARG (0.54) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5479662 | 0.72 | RXFP1 (0.52) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3973842 | 0.72 | RXFP1 (0.52) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4478483 | 0.72 | NPC1 (0.43) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4468392 | 0.72 | RAB9A (0.43) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5099375 | 0.71 | KDM4E (0.72) | NPC1RAB9AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |