Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.70 |
| ▸ | PGR | P06401 | 4/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.67 |
| ▸ | AR | P10275 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290372 | 0.94 | NR3C1 (0.77) | NR3C1PGRNR3C2AR | |
| SCHEMBL4172146 | 0.84 | NR3C1 (0.84) | NR3C1PGRNR3C2AR | |
| SCHEMBL4175142 | 0.83 | NR3C1 (0.74) | NR3C1PGRNR3C2AR | |
| SCHEMBL4172863 | 0.83 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4175513 | 0.83 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4169464 | 0.83 | NR3C1 (0.85) | NR3C1PGRNR3C2AR | |
| SCHEMBL4165601 | 0.82 | NR3C1 (0.85) | NR3C1PGRNR3C2AR | |
| SCHEMBL4167703 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4178899 | 0.82 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4189917 | 0.81 | NR3C1 (0.86) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053239-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2003-01-08 | — | — | EP | claimed |