Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013543 | 0.85 | ESR1 (0.46) | MEN1KMT2ASMN1; SMN2TP53TDP1 | |
| SCHEMBL3830792 | 0.84 | LTA4H (0.49) | MEN1KMT2ASMN1; SMN2TP53TDP1 | |
| SCHEMBL27652847 | 0.79 | LTA4H (0.49) | MEN1KMT2ASMN1; SMN2TDP1LTA4H | |
| SCHEMBL14097352 | 0.79 | MEN1 (0.71) | MEN1KMT2ATDP1LTA4HNR5A1 | |
| SCHEMBL10867956 | 0.78 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2TP53TDP1 | |
| 1-Hydroxy-4-Isopentoxybenzene SCHEMBL2843554 | 0.76 | TDP1 (0.66) | SMN1; SMN2TP53TDP1LTA4HNR5A1 | |
| SCHEMBL11231682 | 0.76 | LTA4H (0.55) | TDP1LTA4HNR5A1MAPK1LMNA | |
| SCHEMBL7692040 | 0.76 | LTA4H (0.52) | KMT2ALTA4HNR5A1L3MBTL1CA12 | |
| SCHEMBL3466988 | 0.74 | CYSLTR2 (0.59) | SMN1; SMN2LTA4HNR5A1MAPT | |
| SCHEMBL3621455 | 0.74 | ESR1 (0.56) | MEN1KMT2ATDP1MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |