Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 2/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990035 | 1.00 | MAPT (0.63) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6698881 | 0.85 | MAPT (0.53) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL646250 | 0.80 | TGM2 (0.52) | MAPTKDM4ESMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL648751 | 0.78 | KDM4E (0.54) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31381207 | 0.77 | KDM4E (0.57) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL18711414 | 0.77 | SMN1; SMN2 (0.70) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16769729 | 0.74 | KDM4E (0.76) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL231236 | 0.74 | MAPT (0.58) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27771333 | 0.73 | KDM4E (0.59) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL485221 | 0.73 | SMN1; SMN2 (0.54) | MAPTKDM4ESMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |