Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6992260 | 0.99 | NPY1R (0.51) | NPY1RTRPV1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL7088429 | 0.94 | TRPV1 (0.46) | NPY1RTRPV1NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL6989924 | 0.94 | TRPV1 (0.46) | NPY1RTRPV1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL6986658 | 0.91 | NPY1R (0.51) | NPY1RTRPV1NPC1POLBMAPT | |
| SCHEMBL7090494 | 0.90 | TRPV1 (0.45) | NPY1RTRPV1NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL6990046 | 0.90 | NPY1R (0.50) | NPY1RTRPV1NPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6988440 | 0.90 | TRPV1 (0.44) | NPY1RTRPV1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL7050479 | 0.89 | NPY1R (0.51) | NPY1RJAK2JAK3CNR2KDR | |
| SCHEMBL7050483 | 0.89 | NPY1R (0.51) | NPY1RJAK2JAK3CNR2KDR | |
| Hydrochloric Acid SCHEMBL6990944 | 0.87 | NPY1R (0.55) | NPY1RNPC1RAB9APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | claimed |
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0915859-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003492-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-01-29 | — | — | WO | disclosed |