Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6990046 | 0.99 | NPY1R (0.50) | NPY1RMEN1NPC1POLBMAPT | |
| SCHEMBL6990201 | 0.91 | NPY1R (0.51) | NPY1RNPC1POLBMAPTNAMPT | |
| Hydrochloric Acid SCHEMBL6992260 | 0.90 | NPY1R (0.51) | NPY1RNPC1POLBMAPTNAMPT | |
| Hydrochloric Acid SCHEMBL6990944 | 0.88 | NPY1R (0.55) | NPY1RMEN1NPC1POLBMAPT | |
| SCHEMBL7090848 | 0.86 | HTR1A (0.55) | NPY1RMEN1NPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6993221 | 0.86 | HTR1A (0.54) | NPY1RMEN1NPC1POLBMAPT | |
| SCHEMBL7091275 | 0.85 | HTR1A (0.54) | NPY1RMEN1NPC1MAPTKMT2A | |
| SCHEMBL7088429 | 0.85 | TRPV1 (0.46) | NPY1RMEN1NPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6989924 | 0.85 | TRPV1 (0.46) | NPY1RMEN1NPC1POLBMAPT | |
| Hydrochloric Acid SCHEMBL6990799 | 0.85 | HTR1A (0.54) | NPY1RMEN1NPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | claimed |
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0915859-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003492-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-01-29 | — | — | WO | disclosed |