Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515531 | 0.93 | CTSK (0.49) | CTSKPRMT5WDR77CTSLCTSS | |
| SCHEMBL6511024 | 0.91 | CTSK (0.52) | CTSK | |
| SCHEMBL6514508 | 0.88 | CTSK (0.53) | CTSKCTSLCTSS | |
| SCHEMBL6512275 | 0.88 | CTSK (0.48) | CTSKPRMT5WDR77CTSLCTSS | |
| SCHEMBL7088824 | 0.86 | CTSK (0.48) | CTSK | |
| SCHEMBL6518424 | 0.85 | CTSK (0.54) | CTSKCTSLCTSS | |
| SCHEMBL6511219 | 0.85 | CTSK (0.51) | CTSK | |
| SCHEMBL6510130 | 0.85 | CTSK (0.51) | CTSKPRMT5WDR77 | |
| SCHEMBL6523396 | 0.85 | CTSK (0.52) | CTSKCTSLCTSS | |
| SCHEMBL6514161 | 0.85 | CTSK (0.54) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358183-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002088106-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2002-11-07 | — | — | WO | disclosed |