Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.40 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990880 | 0.92 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6988979 | 0.91 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6986987 | 0.90 | F10 (0.40) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6995007 | 0.90 | F10 (0.40) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6995249 | 0.84 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6988355 | 0.82 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6993018 | 0.82 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6995018 | 0.81 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6992976 | 0.81 | F10 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6995749 | 0.81 | F10 (0.36) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |