Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994642 | 0.91 | F10 (0.36) | F10PRSS1FPR2FPR1GPR119 | |
| SCHEMBL6987255 | 0.91 | FPR2 (0.37) | F10PRSS1FPR2FPR1GPR119 | |
| SCHEMBL6986987 | 0.91 | F10 (0.40) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL6993018 | 0.89 | F10 (0.47) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL7076657 | 0.87 | F10 (0.40) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7076640 | 0.83 | F10 (0.41) | F10PRSS1FPR2FPR1F2 | |
| SCHEMBL6995380 | 0.82 | F10 (0.46) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL6989984 | 0.82 | F10 (0.46) | F10PRSS1F2KCNH2PRSS2 | |
| SCHEMBL7081032 | 0.82 | F10 (0.41) | F10PRSS1FPR2FPR1F2 | |
| SCHEMBL6995007 | 0.81 | F10 (0.40) | F10PRSS1F2KCNH2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |