Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7990650 | 0.99 | F2 (0.62) | F2RECQLALDH1A1SMN1; SMN2P2RX7 | |
| SCHEMBL6996688 | 0.87 | F2 (0.61) | F2ALDH1A1SMN1; SMN2PRSS1 | |
| SCHEMBL6738372 | 0.83 | F2 (0.47) | F2P2RX7PRSS1 | |
| SCHEMBL6739800 | 0.83 | F2 (0.49) | F2PRSS1 | |
| SCHEMBL7001605 | 0.82 | F2 (0.54) | F2PRSS1 | |
| SCHEMBL7298438 | 0.81 | F2 (0.66) | F2PRSS1 | |
| SCHEMBL6735050 | 0.81 | F2 (0.42) | F2ALDH1A1SMN1; SMN2P2RX7PRSS1 | |
| Hydrochloric Acid SCHEMBL7992275 | 0.81 | F2 (0.54) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7978194 | 0.81 | F2 (0.65) | F2PRSS1 | |
| SCHEMBL6738115 | 0.81 | F2 (0.49) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |