Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996811 | 0.92 | F2 (0.50) | F2PRSS1PRSS2PRSS3RXFP1 | |
| Hydrochloric Acid SCHEMBL7978158 | 0.91 | F2 (0.49) | F2PRSS1PRSS2PRSS3RXFP1 | |
| SCHEMBL6990916 | 0.87 | F2 (0.63) | F2PRSS1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7990650 | 0.86 | F2 (0.62) | F2PRSS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6738372 | 0.82 | F2 (0.47) | F2PRSS1 | |
| SCHEMBL7297314 | 0.78 | F2 (0.39) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7978162 | 0.78 | F2 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7001605 | 0.78 | F2 (0.54) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7002402 | 0.78 | F2 (0.54) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6739800 | 0.77 | F2 (0.49) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |