Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.70 |
| ▸ | ADRA1D | P25100 | 17/20 | 0.70 |
| ▸ | HTR1B | P28222 | 17/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 17/20 | 0.70 |
| ▸ | ADRA1B | P35368 | 17/20 | 0.70 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7720217 | 0.99 | HTR1A (0.69) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6989469 | 0.96 | HTR1A (0.72) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7720168 | 0.95 | HTR1A (0.71) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6994967 | 0.90 | HTR1A (0.73) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722215 | 0.89 | HTR1A (0.72) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7923912 | 0.88 | HTR1A (0.68) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6986368 | 0.86 | HTR1A (0.77) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL6990985 | 0.86 | HTR1A (0.76) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7720229 | 0.86 | HTR1A (0.76) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7720207 | 0.85 | HTR1A (0.75) | HTR1AADRA1DHTR1BADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927184-B1 | 3-SUBSTITUTED PYRIDO 4',3':4,5]THIENO 2,3-D]PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2003-10-22 | — | — | EP | disclosed |