Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679637 | 0.91 | F10 (0.56) | F10HTR1AHTR7DRD2HTR6 | |
| SCHEMBL6991426 | 0.84 | F10 (0.59) | F10HTR1AHTR7 | |
| SCHEMBL4680171 | 0.82 | F10 (0.74) | F10 | |
| SCHEMBL2699564 | 0.80 | F10 (0.59) | F10HTR1AHTR7DRD2HTR6 | |
| SCHEMBL4684603 | 0.77 | F10 (0.58) | F10HTR1AHTR7DRD2HTR6 | |
| SCHEMBL6986018 | 0.75 | F10 (0.68) | F10 | |
| SCHEMBL6712834 | 0.74 | F10 (0.69) | F10 | |
| SCHEMBL18131025 | 0.74 | F10 (0.53) | F10HTR1AHTR7DRD2HTR6 | |
| SCHEMBL6991402 | 0.71 | F10 (0.56) | F10HTR1AHTR7DRD2HTR6 | |
| SCHEMBL6989398 | 0.71 | F10 (0.35) | F10HTR1AHTR7DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |