Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991594 | 0.88 | AVPR1A (0.67) | AVPR1ATP53AVPR1BMEN1KMT2A | |
| SCHEMBL6989154 | 0.87 | AVPR1A (0.73) | AVPR1ATP53AVPR1BMEN1KMT2A | |
| SCHEMBL6992887 | 0.87 | AVPR1A (0.60) | AVPR1AAVPR1BPOLBMAPTAVPR2 | |
| SCHEMBL6984078 | 0.86 | AVPR1A (0.69) | AVPR1AAVPR1BMEN1KMT2AAVPR2 | |
| SCHEMBL6992362 | 0.84 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989817 | 0.84 | AVPR1A (0.66) | AVPR1ATP53AVPR1BMEN1KMT2A | |
| SCHEMBL6987519 | 0.83 | AVPR1A (0.63) | AVPR1ATP53AVPR1BAVPR2LMNA | |
| SCHEMBL6989965 | 0.83 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2LMNAOXTR | |
| SCHEMBL6992930 | 0.83 | AVPR1A (0.63) | AVPR1AAVPR1BLMNA | |
| SCHEMBL6991880 | 0.83 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |