Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994643 | 0.91 | AVPR1A (0.66) | AVPR1ARAB9AAVPR1B | |
| SCHEMBL6992930 | 0.88 | AVPR1A (0.63) | AVPR1AAVPR1B | |
| SCHEMBL8799494 | 0.86 | AVPR1A (0.65) | AVPR1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL6989965 | 0.86 | AVPR1A (0.60) | AVPR1AAVPR1B | |
| SCHEMBL6992370 | 0.86 | AVPR1A (0.67) | AVPR1AAVPR1B | |
| SCHEMBL6989784 | 0.86 | AVPR1A (0.67) | AVPR1ARAB9ANPC1MAPTAVPR1B | |
| SCHEMBL6984078 | 0.85 | AVPR1A (0.69) | AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL6991577 | 0.85 | AVPR1A (0.68) | AVPR1ARAB9AAVPR1B | |
| SCHEMBL6993624 | 0.85 | AVPR1A (0.66) | AVPR1AAVPR1B | |
| SCHEMBL6992362 | 0.85 | AVPR1A (0.71) | AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |