Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991625 | 1.00 | USP30 (0.49) | USP30KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL6992769 | 0.83 | USP30 (0.54) | USP30KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL6992765 | 0.83 | USP30 (0.54) | USP30KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL19037361 | 0.78 | USP30 (0.58) | USP30KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL19041868 | 0.78 | USP30 (0.58) | USP30KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL408174 | 0.78 | USP30 (0.58) | USP30KDM4EPKMGPR119ALDH1A1 | |
| SCHEMBL1769219 | 0.74 | USP30 (0.71) | USP30KDM4EPKMGPR119JAK2 | |
| SCHEMBL21409063 | 0.74 | USP30 (0.71) | USP30KDM4EPKMGPR119JAK2 | |
| SCHEMBL5153452 | 0.74 | USP30 (0.71) | USP30KDM4EPKMGPR119JAK2 | |
| SCHEMBL23465733 | 0.74 | GPR119 (0.62) | GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |