Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.74 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.66 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | OXTR | P30559 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989322 | 0.90 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2MEN1NPC1 | |
| SCHEMBL6984078 | 0.89 | AVPR1A (0.69) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL6988119 | 0.89 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6993534 | 0.87 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6992362 | 0.87 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6986061 | 0.86 | AVPR1A (0.77) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6988967 | 0.85 | AVPR1A (0.69) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL6991584 | 0.85 | AVPR1A (0.72) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL6987256 | 0.85 | AVPR1A (0.69) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6991644 | 0.84 | AVPR1A (0.73) | AVPR1AAVPR1BAVPR2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |