Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.86 |
| ▸ | PPARG | P37231 | 16/20 | 0.86 |
| ▸ | PPARD | Q03181 | 8/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105696 | 0.97 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL6699850 | 0.95 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5098886 | 0.93 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6996508 | 0.92 | PPARA (0.87) | PPARAPPARGPPARD | |
| SCHEMBL5105881 | 0.91 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5125943 | 0.91 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6695462 | 0.91 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5111844 | 0.91 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL6702560 | 0.91 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL6989361 | 0.90 | PPARA (0.71) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |