Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.87 |
| ▸ | PPARG | P37231 | 16/20 | 0.87 |
| ▸ | PPARD | Q03181 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099380 | 0.96 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL5098724 | 0.93 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6991817 | 0.92 | PPARA (0.86) | PPARAPPARGPPARD | |
| SCHEMBL6699850 | 0.89 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5105696 | 0.89 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5103042 | 0.89 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL5106173 | 0.88 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL5098579 | 0.88 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL5105881 | 0.87 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6702557 | 0.87 | PPARA (0.69) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |