Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.65 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.65 |
| ▸ | F2 | P00734 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
| ▸ | PROC | P04070 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995434 | 0.87 | F10 (0.64) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6999310 | 0.85 | F10 (0.61) | F10PRSS1PRSS2PRSS3F2 | |
| Acetic Acid SCHEMBL7080775 | 0.85 | F10 (0.64) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7115966 | 0.82 | F10 (0.70) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL12132476 | 0.79 | F10 (0.75) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL7451947 | 0.79 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6989121 | 0.79 | F10 (0.57) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7681967 | 0.79 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7451943 | 0.79 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7688293 | 0.78 | F10 (1.00) | F10PRSS1F2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | F5, CCNY, F2 | F10 5/4885PRSS1 398/4885PRSS2 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.